Comment Article uri icon

Overview

MeSH Major

  • Cerebrospinal Fluid
  • Pathology, Clinical
  • Subarachnoid Hemorrhage

abstract

  • This simple laboratory study would be expected to maximize agreement relative to clinical practice. Although non-color-blind female observers significantly outperformed non-color-blind male observers, both intraobserver agreement and interobserver agreement for xanthochromia were prohibitively poor regardless of sex or illumination. Yellow was most frequently misclassified, 88% as clear (ie, true positives were commuted to false negatives). Xanthochromia is therefore highly unreliable for subarachnoid hemorrhage diagnosis and computed tomography validation. The Walton rule requires urgent clinical revalidation.

publication date

  • January 2014

Research

keywords

  • Article

Identity

Digital Object Identifier (DOI)

  • 10.1227/NEU.0000000000000291

Additional Document Info

start page

  • 395

end page

  • 9; discussion 399-400

volume

  • 74

number

  • 4