Acute kidney injury due to tubular intraluminal monoclonal light chain crystals mimicking acute pyelonephritis Academic Article uri icon

Overview

MeSH Major

  • Acute Kidney Injury
  • Bence Jones Protein
  • Immunoglobulin lambda-Chains
  • Kidney Neoplasms
  • Kidney Tubules
  • Multiple Myeloma
  • Neutrophils

abstract

  • Tubular intraluminal inflammatory cells may be seen in kidney biopsies of patients with pyelonephritis, cell-mediated transplant rejection, autoimmune tubulointerstitial nephritis, allergic reactions, or in association with monoclonal light chain casts. When casts in a native kidney are primarily composed of granulocytes, the cause is most commonly acute pyelonephritis due to an ascending bacterial urinary tract infection. We report a 57-year-old man with acute kidney injury and an intense intraluminal neutrophil response to monoclonal lambda light chain crystal containing casts.

publication date

  • March 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.3109/0886022X.2013.844643

PubMed ID

  • 24152144

Additional Document Info

start page

  • 300

end page

  • 5

volume

  • 36

number

  • 2