Role of radiation therapy for renal tumors Review uri icon


MeSH Major

  • DNA, Mitochondrial
  • Echinodermata
  • NADH Dehydrogenase


  • Renal cell carcinoma (RCC) is an aggressive malignancy that carries a poor prognosis, especially in patients presenting with advanced stage. Primary treatment for localized RCC is surgical resection however, a significant number of patients still develop locoregional and distant metastasis after curative resection. In metastatic disease, radiation therapy (RT) has been used for palliation routinely for brain and other extracranial lesions with respectable response rates. However, RT for primary RCC has questionable benefit. In this article, the authors discuss the evidence with regards to the role of RT in primary RCC either as a primary treatment, adjuvant treatment, or preoperatively to improve resection outcomes. In addition, novel RT techniques such as stereotactic body radiation therapy and its use in RCC management are also addressed. Finally, the authors discuss the techniques and doses of RT for primary RCC.

publication date

  • January 2014



  • Review



  • eng

PubMed Central ID

  • PMC3930657

Digital Object Identifier (DOI)

  • 10.1055/s-0033-1363847

PubMed ID

  • 24596444

Additional Document Info

start page

  • 86

end page

  • 90


  • 31


  • 1