Coronary artery disease and cardiomyopathy
Genome-Wide Association Study
Hypertrophy, Left Ventricular
Polymorphism, Single Nucleotide
Shab Potassium Channels
Cardiovascular disease (CVD) is the leading cause of death in patients with type 2 diabetes. Epidemiological studies have shown that diabetes mellitus is a potent independent risk factor for cardiovascular disease.1,2 It has been recognized for several decades that diabetic patients have a 2- to 3-fold higher risk for CVD than their nondiabetic counterparts. CVD accounts for up to 80% of deaths in patients with diabetes, approximately 75% of which are due to ischemic heart disease. More than 25% of diabetic patients have evidence of CVD at diagnosis. Therefore, the American Heart Association has stated that diabetes is a cardiovascular disease. © 2010 Springer-Verlag US.
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