Renal cell carcinoma: Molecular targets and clinical applications Book uri icon


MeSH Major

  • Antineoplastic Agents
  • Boronic Acids
  • Carcinoma, Renal Cell
  • Kidney Medulla
  • Kidney Neoplasms
  • Pyrazines


  • In the second edition of their critically acclaimed book, Ronald Bukowski, Robert Motzer, and Robert Figlin have thoroughly updated and expanded their survey of clinical, biological and pathological management of localized and advanced renal cell carcinoma. A panel of internationally renowned contributors explores the latest developments in molecular genetics, focusing on the novel targets that have been discovered in epithelial renal tumors. The discussion includes the specific biology of selected target molecules or receptors and the various agents that inhibit these targets, including full chapters devoted to drugs that selectively inhibit receptor tyrosine kinases, such as sunitinib and axitinib. Further attention is paid to leading-edge strategies that target and inhibit tumor associated angiogenesis and block the vascular endothelial growth factor pathway. Comprehensive and authoritative, Renal Cell Carcinoma: Molecular Targets and Clinical Applications, Second Edition is the definitive text on the rapidly evolving landscape of experimental therapeutics, written and edited by the pioneers of the field. © Humana Press, a part of Springer Science+Business Media, LLC 2009. All rights reserved.

publication date

  • December 2009



  • Book


Digital Object Identifier (DOI)

  • 10.1007/978-1-59745-332-5

International Standard Book Number (ISBN) 13

  • 9781588297372

Additional Document Info

start page

  • 1

end page

  • 507