Depression epidemiology and its treatment evolution. Academic Article uri icon

Overview

MeSH Major

  • Antidepressive Agents
  • Depression

abstract

  • Approximately 1 in 5 US adults have at least one episode of major depression in their lifetime. Of those who do, the majority will relapse over the long term and many will have psychosocial disabilities and reduced functioning. Over the past century, a range of medications have been developed to treat depression, although some effective medications have been superseded by newer treatments with an improved safety and tolerability profile. A reconsideration of some older medications is warranted until agents with truly novel mechanisms of action and good safety and tolerability profiles are available.

publication date

  • October 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 23140659

Additional Document Info

start page

  • e29

volume

  • 73

number

  • 10