Integrating VA's NDF-RT drug terminology with PharmGKB: preliminary results. Academic Article uri icon

Overview

MeSH

  • Computational Biology
  • Disease
  • Drug Therapy
  • Humans
  • Pharmacokinetics
  • Terminology as Topic
  • United States
  • United States Department of Veterans Affairs

MeSH Major

  • Knowledge Bases
  • Pharmaceutical Preparations
  • Pharmacogenetics

abstract

  • Biomedical terminology and vocabulary standards play an important role in enabling consistent, comparable, and meaningful sharing of data within and across institutional boundaries, as well as ensuring semantic interoperability. The Veterans Affairs (VA) National Drug File Reference Terminology (NDF-RT) is a federally recommended standardized terminology resource encompassing medications, ingredients, and a hierarchy for high-level drug classes. In this study, we investigate the drug-disease relationships in NDF-RT and determine how PharmGKB can be leveraged to augment NDF-RT, and vice-versa. Our preliminary results indicate that with additional curation and analyses, information contained in both knowledge resources can be mutually integrated.

publication date

  • 2012

has subject area

  • Computational Biology
  • Disease
  • Drug Therapy
  • Humans
  • Knowledge Bases
  • Pharmaceutical Preparations
  • Pharmacogenetics
  • Pharmacokinetics
  • Terminology as Topic
  • United States
  • United States Department of Veterans Affairs

Research

keywords

  • Journal Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3909655

PubMed ID

  • 22174295

Additional Document Info

start page

  • 400

end page

  • 409