IQCB1 and PDE6B mutations cause similar early onset retinal degenerations in two closely related terrier dog breeds. Academic Article uri icon

Overview

MeSH Major

  • Calmodulin-Binding Proteins
  • Cyclic Nucleotide Phosphodiesterases, Type 6
  • DNA
  • Genetic Predisposition to Disease
  • Photoreceptor Cells, Vertebrate
  • Retinal Degeneration

abstract

  • Identification of the mutations responsible for these two early-onset retinal degenerations provides new large animal models for comparative disease studies and evaluation of potential therapeutic approaches for the homologous human diseases.

publication date

  • October 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3809947

PubMed ID

  • 24045995

Additional Document Info

start page

  • 7005

end page

  • 19

volume

  • 54

number

  • 10