Kidney cancer in 2013: From molecular understanding to clinical advances Article uri icon

Overview

MeSH Major

  • Carcinoma, Renal Cell
  • Hypoxia-Inducible Factor 1
  • Kidney Neoplasms
  • Receptors, CXCR4
  • Transcription Factors
  • Von Hippel-Lindau Tumor Suppressor Protein

abstract

  • Big data and computational biology brought to the forefront a number of potential actionable mutations and drug targets in clear cell renal cell carcinoma in 2013. As we continue to unravel the molecular underpinnings of tumorigenesis and progression, the clinical benefits will eventually be reaped.

publication date

  • January 2014

Research

keywords

  • Article

Identity

Digital Object Identifier (DOI)

  • 10.1038/nrurol.2013.307

Additional Document Info

start page

  • 77

end page

  • 9

volume

  • 11

number

  • 2