Evaluation of arginine deiminase treatment in melanoma xenografts using 18F-FLT PET
Academic Article
Overview
MeSH Major
Antineoplastic Agents
Dideoxynucleosides
Hydrolases
Melanoma
abstract
The specific pharmacological properties of ADI preclude using (18)F-FLT to evaluate clinical response in melanoma and argue for further studies to explore the use of other clinically applicable PET tracers in ADI treatment.