Granular Cell Tumor
Soft Tissue Neoplasms
The skin is a complex organ system consisting of a sophisticated network of nerve fibers and specialized sensory structures. Cutaneous nerves release neuropeptides and neurohormones into the local milieu in response to internal and external stimuli. Many appear to serve an immunoregulatory role. Neuropeptides play a role in the pathophysiology of common skin diseases such as atopic dermatitis and psoriasis. TSubstance P and calcitonin gene-related peptide are among the most prevalent and multifunctional neuropeptides in the skin. © 2008 Springer London.
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