Non-high-density lipoprotein cholesterol, guideline targets, and population percentiles for secondary prevention in 1.3 million adults: The VLDL-2 study (very large database of lipids) Academic Article uri icon

Overview

MeSH Major

  • Cardiovascular Diseases
  • Cholesterol, LDL
  • Hypolipidemic Agents
  • Practice Guidelines as Topic
  • Secondary Prevention

abstract

  • There is significant patient-level discordance between non-HDL-C and LDL-C percentiles at lower LDL-C and higher triglyceride levels, which has implications for the treatment of high-risk patients. Current non-HDL-C cutpoints for high-risk patients may need to be lowered to match percentiles of LDL-C cutpoints. Relatively small absolute reductions in non-HDL-C cutpoints result in substantial reclassification of patients to higher treatment categories with potential implications for risk assessment and treatment.

publication date

  • November 19, 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.jacc.2013.07.045

PubMed ID

  • 23973689

Additional Document Info

start page

  • 1960

end page

  • 1965

volume

  • 62

number

  • 21