Prostate cancer progression correlates with increased humoral immune response to a human endogenous retrovirus GAG protein Academic Article uri icon

Overview

MeSH Major

  • Endogenous Retroviruses
  • Gene Products, gag
  • Prostatic Neoplasms

abstract

  • Preferential expression of GAG-HERV-K ch22q11.23 in prostate cancer tissue and increased frequency of autoantibodies observed in patients with advanced prostate cancer make this protein one of the first bona fide retroviral cancer antigens in humans, with potential as a biomarker for progression and biochemical recurrence rate of prostate cancer. Clin Cancer Res; 19(22); 6112-25. ©2013 AACR.

publication date

  • November 15, 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-12-3580

PubMed ID

  • 24081977

Additional Document Info

start page

  • 6112

end page

  • 25

volume

  • 19

number

  • 22