The International Society for bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders Academic Article uri icon

Overview

MeSH Major

  • Antidepressive Agents
  • Bipolar Disorder

abstract

  • Because of limited data, the task force could not make broad statements endorsing antidepressant use but acknowledged that individual bipolar patients may benefit from antidepressants. Regarding safety, serotonin reuptake inhibitors and bupropion may have lower rates of manic switch than tricyclic and tetracyclic antidepressants and norepinephrine-serotonin reuptake inhibitors. The frequency and severity of antidepressant-associated mood elevations appear to be greater in bipolar I than bipolar II disorder. Hence, in bipolar I patients antidepressants should be prescribed only as an adjunct to mood-stabilizing medications.

authors

publication date

  • November 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4091043

Digital Object Identifier (DOI)

  • 10.1176/appi.ajp.2013.13020185

PubMed ID

  • 24030475

Additional Document Info

start page

  • 1249

end page

  • 62

volume

  • 170

number

  • 11