Prevalence and co-occurrence of actionable genomic alterations in high-grade bladder cancer Academic Article uri icon

Overview

MeSH Major

  • DNA Copy Number Variations
  • Mutation
  • Urinary Bladder Neoplasms

abstract

  • High-grade bladder cancer possesses substantial genomic heterogeneity. The majority of tumors harbor potentially tractable genomic alterations that may predict for response to target-selective agents. Given the genomic diversity of bladder cancers, optimal development of target-specific agents will require pretreatment genomic characterization.

publication date

  • September 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3753703

Digital Object Identifier (DOI)

  • 10.1200/JCO.2012.46.5740

PubMed ID

  • 23897969

Additional Document Info

start page

  • 3133

end page

  • 40

volume

  • 31

number

  • 25