The Cancer Genome Atlas Pan-Cancer analysis project. Academic Article uri icon

Overview

MeSH

  • Gene Expression Profiling
  • Humans

MeSH Major

  • Genome
  • Neoplasms

abstract

  • The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile.

authors

publication date

  • October 2013

has subject area

  • Gene Expression Profiling
  • Genome
  • Humans
  • Neoplasms

Research

keywords

  • Journal Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3919969

Digital Object Identifier (DOI)

  • 10.1038/ng.2764

PubMed ID

  • 24071849

Additional Document Info

start page

  • 1113

end page

  • 1120

volume

  • 45

number

  • 10