Partial protection against multiple rt-shiv162p3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the nnrti mc1220
Natural Orifice Endoscopic Surgery
Tomography, Optical Coherence
An MC1220-releasing SEVR partially protected macaques from vaginal challenge. Such ring devices are a practical method for providing sustained, coitally independent protection against vaginal exposure to HIV-1.