Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma Academic Article uri icon

Overview

MeSH Major

  • Azacitidine
  • DNA Methylation
  • DNA Modification Methylases
  • Lymphoma, Large B-Cell, Diffuse

abstract

  • The problem of chemoresistant DLBCL remains the most urgent challenge in the clinical management of patients with this disease. We describe a mechanism-based approach toward the rational translation of DNMTIs for the treatment of high-risk DLBCL.

publication date

  • September 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3770813

Digital Object Identifier (DOI)

  • 10.1158/2159-8290.CD-13-0117

PubMed ID

  • 23955273

Additional Document Info

start page

  • 1002

end page

  • 19

volume

  • 3

number

  • 9