Phase II study of lutetium-177-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for metastatic castration-resistant prostate cancer Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Monoclonal
  • Antigens, Surface
  • Glutamate Carboxypeptidase II
  • Prostatic Neoplasms, Castration-Resistant

abstract

  • A single dose of (177)Lu-J591 was well tolerated with reversible myelosuppression. Accurate tumor targeting and PSA responses were seen with evidence of dose response. Imaging biomarkers seem promising.

publication date

  • September 15, 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3778101

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-13-0231

PubMed ID

  • 23714732

Additional Document Info

start page

  • 5182

end page

  • 91

volume

  • 19

number

  • 18