Extra-articular knee lesion with high fluorodeoxyglucose-uptake on positron emission tomography Academic Article uri icon


MeSH Major

  • Fluorodeoxyglucose F18
  • Knee
  • Positron-Emission Tomography
  • Radiopharmaceuticals
  • Synovitis, Pigmented Villonodular
  • Tendons


  • Pigmented villonodular synovitis (PVNS) is an uncommon musculoskeletal tumor that is typically benign and often diagnosed radiologically by magnetic resonance imaging (MRI). Fluorodeoxyglucose (FDG)-uptake positron emission tomography (PET) is an imaging tool primarily used in oncology to evaluate malignancy. FDG measures metabolic activity with standardized uptake value (SUV). A high SUV is suggestive of malignancy. We report a case of PVNS detected incidentally by FDG-PET as an extracapsular mass adherent to vastus medialis tendon with a high SUV of 15.1. Given the patient's history of cancer and the high SUV, the lesion was initially considered a malignancy. The objective of this case report is to illustrate that even a high-SUV mass detected with PET imaging does not necessarily indicate malignancy, and thus a benign lesion can also demonstrate such elevated signal.

publication date

  • June 2013



  • Academic Article



  • eng

PubMed ID

  • 24032621

Additional Document Info

start page

  • 170

end page

  • 4


  • 71


  • 2