Highly Cross-Linked Polyethylene May Not Have an Advantage in Total Knee Arthroplasty Review uri icon


MeSH Major

  • Acetabulum
  • Arthroplasty, Replacement, Hip
  • Pelvic Bones


  • Based on our review, we concluded that (1) the material properties of XLPE reduce adhesive and abrasive wear, but not the risk of crack propagation, deformation, pitting, and delamination found in TKR; (2) wear-induced osteolysis in TKR has not been found to be a major cause of failure at long-term follow-up; (3) mid-term follow-up studies show no difference in any recorded outcome measure between conventional PE and XLPE; and (4) XLPE is two to four times the cost of conventional PE without an improvement in clinical or radiographic outcomes. For these reasons, we currently cannot recommend the use of XLPE in TKR. Conventional compression-molded polyethylene with its outstanding long-term results should remain the material of choice in TKR.

publication date

  • October 2013



  • Review



  • eng

PubMed Central ID

  • PMC3772158

Digital Object Identifier (DOI)

  • 10.1007/s11420-013-9352-x

PubMed ID

  • 24426878

Additional Document Info

start page

  • 264

end page

  • 9


  • 9


  • 3