Spectrum of Ocular Manifestations in CLN2-Associated Batten (Jansky-Bielschowsky) Disease Correlate with Advancing Age and Deteriorating Neurological Function Academic Article uri icon

Overview

MeSH Major

  • Eye Diseases
  • Neuronal Ceroid-Lipofuscinoses

abstract

  • Ophthalmic manifestations of LINCL correlate closely with the degree of neurological function and the age of the patient. The newly established LINCL Ophthalmic Scale may serve as an objective marker of LINCL severity and disease progression, and may be valuable in the evaluation of novel therapeutic strategies for LINCL, including gene therapy.

publication date

  • August 28, 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3756041

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0073128

PubMed ID

  • 24015292

Additional Document Info

start page

  • e73128

volume

  • 8

number

  • 8