Molecular interactions in the development of brain metastases Review uri icon

Overview

MeSH Major

  • Brain Neoplasms

abstract

  • Brain metastases are a much-feared complication of cancer. The development of brain metastases requires a malignant cell to acquire characteristics that facilitate dissemination away from the primary site, entrance into the nervous system, and establishment in the brain. This review summarizes recent work focused on the molecular derangements leading to brain metastases and outlines areas in need of greater understanding.

publication date

  • September 3, 2013

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC3759957

Digital Object Identifier (DOI)

  • 10.3390/ijms140817157

PubMed ID

  • 23965978

Additional Document Info

start page

  • 17157

end page

  • 67

volume

  • 14

number

  • 8