Lumpectomy plus tamoxifen with or without irradiation in women age 70 years or older with early breast cancer: long-term follow-up of CALGB 9343. Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents, Hormonal
  • Biomarkers, Tumor
  • Breast Neoplasms
  • Mastectomy, Segmental
  • Receptors, Estrogen
  • Tamoxifen

abstract

  • With long-term follow-up, the previously observed small improvement in locoregional recurrence with the addition of radiation therapy remains. However, this does not translate into an advantage in OS, distant disease-free survival, or breast preservation. Depending on the value placed on local recurrence, Tam remains a reasonable option for women age ≥ 70 years with ER-positive early-stage breast cancer.

publication date

  • July 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3691356

Digital Object Identifier (DOI)

  • 10.1200/JCO.2012.45.2615

PubMed ID

  • 23690420

Additional Document Info

start page

  • 2382

end page

  • 7

volume

  • 31

number

  • 19