An evaluation of the NQF Quality Data Model for representing Electronic Health Record driven phenotyping algorithms. Academic Article Article uri icon

Overview

MeSH

  • Biomedical Research
  • Humans
  • Natural Language Processing
  • Programming Languages
  • Quality Control

MeSH Major

  • Algorithms
  • Electronic Health Records
  • Phenotype

abstract

  • The development of Electronic Health Record (EHR)-based phenotype selection algorithms is a non-trivial and highly iterative process involving domain experts and informaticians. To make it easier to port algorithms across institutions, it is desirable to represent them using an unambiguous formal specification language. For this purpose we evaluated the recently developed National Quality Forum (NQF) information model designed for EHR-based quality measures: the Quality Data Model (QDM). We selected 9 phenotyping algorithms that had been previously developed as part of the eMERGE consortium and translated them into QDM format. Our study concluded that the QDM contains several core elements that make it a promising format for EHR-driven phenotyping algorithms for clinical research. However, we also found areas in which the QDM could be usefully extended, such as representing information extracted from clinical text, and the ability to handle algorithms that do not consist of Boolean combinations of criteria.

publication date

  • 2012

has subject area

  • Algorithms
  • Biomedical Research
  • Electronic Health Records
  • Humans
  • Natural Language Processing
  • Phenotype
  • Programming Languages
  • Quality Control

Research

keywords

  • Evaluation Studies
  • Journal Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3540514

PubMed ID

  • 23304366

Additional Document Info

start page

  • 911

end page

  • 920

volume

  • 2012