Neutrophil gelatinase-associated lipocalin (NGAL) levels in response to unilateral renal ischaemia in a novel pilot two-kidney porcine model Academic Article uri icon

Overview

MeSH Major

  • Acute Kidney Injury
  • Disease Models, Animal

abstract

  • We have developed a promising novel small-scale pilot surgical model that allowed the evaluation of bilateral RU function separately during and after unilateral renal ischaemia. The induction of unilateral renal ischaemia corresponds with physiological changes in both the ischaemic and contralateral RU. AKI as measured by increases in NGAL and decreased renal function as measured by decreases in CC, are specific to the RU exposed to ischaemia.

publication date

  • August 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4235973

Digital Object Identifier (DOI)

  • 10.1111/bju.12066

PubMed ID

  • 23510358

Additional Document Info

start page

  • 517

end page

  • 25

volume

  • 112

number

  • 4