Bringing optogenetics to the synapse Article uri icon

Overview

MeSH Major

  • Chromophore-Assisted Light Inactivation
  • Neural Inhibition
  • Optogenetics
  • Synapses
  • Synaptic Transmission

abstract

  • In this issue of Neuron, Lin et al. (2013) describe InSynC, an optogenetic approach that utilizes chromophore-assisted light inactivation (CALI) to inactivate presynaptic neurotransmitter release proteins VAMP2 and synaptophysin. InSynC selectively reduces synaptic transmission in illuminated regions in vitro and in vivo.

publication date

  • July 24, 2013

Research

keywords

  • Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/j.neuron.2013.07.009

Additional Document Info

start page

  • 209

end page

  • 10

volume

  • 79

number

  • 2