Evidence of purinergic neurotransmission in isolated, intact horse sweat glands Academic Article uri icon

Overview

MeSH Major

  • Horses
  • Receptors, Purinergic
  • Sweat Glands
  • Synaptic Transmission

abstract

  • The results show that it is possible to investigate stimulus-secretion coupling mechanisms by fluorescence imaging in equine sweat glands that have been isolated from fresh skin samples. Such isolated glands retain functional β2-adrenoceptors and P2Y purinergic receptors that couple to a calcium-signalling pathway. Using isolated, intact sweat glands therefore offers a very useful model for the further study of secretory processes in equine sweat glands, and using this experimental approach could facilitate a better understanding of how these mechanisms are affected in equine anhidrosis.

publication date

  • August 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1111/vde.12042

PubMed ID

  • 23751108

Additional Document Info

start page

  • 398

end page

  • 403, e85-6

volume

  • 24

number

  • 4