Explicit consideration of baseline factors to assess recombinant tissue-type plasminogen activator response with respect to race and sex
African Continental Ancestry Group
European Continental Ancestry Group
Tissue Plasminogen Activator
Matching for key baseline factors indicated that race and sex influence outcome most strikingly in black women who demonstrated poorest outcomes after rtPA. This finding supports the hypothesis that poor response to rtPA, rather than differences in baseline conditions, contributes to the worse outcome. This finding requires prospective confirmation.