Explicit consideration of baseline factors to assess recombinant tissue-type plasminogen activator response with respect to race and sex Academic Article uri icon

Overview

MeSH Major

  • African Continental Ancestry Group
  • European Continental Ancestry Group
  • Fibrinolytic Agents
  • Sex Factors
  • Stroke
  • Tissue Plasminogen Activator

abstract

  • Matching for key baseline factors indicated that race and sex influence outcome most strikingly in black women who demonstrated poorest outcomes after rtPA. This finding supports the hypothesis that poor response to rtPA, rather than differences in baseline conditions, contributes to the worse outcome. This finding requires prospective confirmation.

publication date

  • June 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5535075

Digital Object Identifier (DOI)

  • 10.1161/STROKEAHA.113.001116

PubMed ID

  • 23674524

Additional Document Info

start page

  • 1525

end page

  • 31

volume

  • 44

number

  • 6