Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4 Academic Article uri icon

Overview

MeSH Major

  • Carbon
  • Pancreatic Neoplasms

abstract

  • This is the largest genetic study to date to examine the relation between germline variations in OCM-related genes polymorphisms and the risk of PanCa. Suggestive evidence for an association between polymorphisms and PanCa was observed among the cohort-nested studies, but this did not replicate in the case-control studies. Our results do not strongly support the hypothesis that genes related to OCM play a role in pancreatic carcinogenesis.

authors

publication date

  • March 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4127987

Digital Object Identifier (DOI)

  • 10.1007/s10552-012-0138-0

PubMed ID

  • 23334854

Additional Document Info

start page

  • 595

end page

  • 602

volume

  • 24

number

  • 3