Laser microdissection and proteomic analysis of amyloidosis, cryoglobulinemic GN, fibrillary GN, and immunotactoid glomerulopathy Academic Article uri icon

Overview

MeSH Major

  • Amyloidosis
  • Cryoglobulinemia
  • Glomerulonephritis
  • Kidney Glomerulus
  • Laser Capture Microdissection
  • Proteins
  • Proteomics

abstract

  • Based on the spectra numbers, the study shows that the relative amount of apolipoprotein E to Ig light-chain C region/amyloidogenic proteins or Ig γ-1 chain C region is associated with the organization of the deposits in amyloidosis, fibrillary GN, and immunotactoid glomerulopathy. However, the absence of apolipoprotein E correlates with the lack of fibrillar deposits in cryoglobulinemic GN.

publication date

  • June 7, 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3675846

Digital Object Identifier (DOI)

  • 10.2215/CJN.07030712

PubMed ID

  • 23411427

Additional Document Info

start page

  • 915

end page

  • 21

volume

  • 8

number

  • 6