Gastric cancer, version 2.2013 Review uri icon

Overview

MeSH Major

  • Stomach Neoplasms

abstract

  • The NCCN Clinical Practice Guidelines in Oncology for Gastric Cancer provide evidence- and consensus-based recommendations for a multidisciplinary approach for the management of patients with gastric cancer. For patients with resectable locoregional cancer, the guidelines recommend gastrectomy with a D1+ or a modified D2 lymph node dissection (performed by experienced surgeons in high-volume centers). Postoperative chemoradiation is the preferred option after complete gastric resection for patients with T3-T4 tumors and node-positive T1-T2 tumors. Postoperative chemotherapy is included as an option after a modified D2 lymph node dissection for this group of patients. Trastuzumab with chemotherapy is recommended as first-line therapy for patients with HER2-positive advanced or metastatic cancer, confirmed by immunohistochemistry and, if needed, by fluorescence in situ hybridization for IHC 2+.

authors

publication date

  • May 27, 2013

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 23667204

Additional Document Info

start page

  • 531

end page

  • 46

volume

  • 11

number

  • 5