Characteristics of lung cancers harboring NRAS mutations Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • GTP Phosphohydrolases
  • Lung Neoplasms
  • Membrane Proteins

abstract

  • NRAS mutations define a distinct subset of lung cancers (∼1%) with potential sensitivity to MEK inhibitors. Although NRAS mutations are more common in current/former smokers, the types of mutations are not those classically associated with smoking.

publication date

  • May 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3643999

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-12-3173

PubMed ID

  • 23515407

Additional Document Info

start page

  • 2584

end page

  • 91

volume

  • 19

number

  • 9