Assessment of disease severity in late infantile neuronal ceroid lipofuscinosis using multiparametric MR imaging Academic Article uri icon

Overview

MeSH Major

  • Brain
  • Magnetic Resonance Imaging
  • Neuronal Ceroid-Lipofuscinoses
  • Severity of Illness Index

abstract

  • The multiparametric disease-severity score obtained from the combination of ADC, %CSF, and NAA/Cr whole-brain MR imaging techniques provided a robust measure of disease severity, which may be useful in clinical therapeutic trials of LINCL in which an objective assessment of therapeutic response is desired.

publication date

  • April 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3644851

Digital Object Identifier (DOI)

  • 10.3174/ajnr.A3297

PubMed ID

  • 23042927

Additional Document Info

start page

  • 884

end page

  • 9

volume

  • 34

number

  • 4