Multicompartment mesoporous silica nanoparticles with branched shapes: An epitaxial growth mechanism Academic Article uri icon


MeSH Major

  • Chemistry Techniques, Synthetic
  • Nanoparticles
  • Silicon Dioxide


  • Mesoporous nanomaterials have attracted widespread interest because of their structural versatility for applications including catalysis, separation, and nanomedicine. We report a one-pot synthesis method for a class of mesoporous silica nanoparticles (MSNs) containing both cubic and hexagonally structured compartments within one particle. These multicompartment MSNs (mc-MSNs) consist of a core with cage-like cubic mesoporous morphology and up to four branches with hexagonally packed cylindrical mesopores epitaxially growing out of the cubic core vertices. The extent of cylindrical mesostructure growth can be controlled via a single additive in the synthesis. Results suggest a path toward high levels of architectural complexity in locally amorphous, mesostructured nanoparticles, which could enable tuning of different pore environments of the same particle for specific chemistries in catalysis or drug delivery.

publication date

  • April 19, 2013



  • Academic Article



  • eng

Digital Object Identifier (DOI)

  • 10.1126/science.1231391

PubMed ID

  • 23599490

Additional Document Info

start page

  • 337

end page

  • 41


  • 340


  • 6130