An optimized algorithm for detecting and annotating regional differential methylation Academic Article uri icon

Overview

MeSH Major

  • Algorithms
  • DNA Methylation
  • Molecular Sequence Annotation

abstract

  • Our weighted optimization algorithm eDMR for calling DMRs extends an established DMR R pipeline (methylKit) and provides a needed resource in epigenomics. Our method enables an accurate and scalable way of finding DMRs in high-throughput methylation sequencing experiments. eDMR is available for download at http://code.google.com/p/edmr/.

publication date

  • April 10, 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3622633

Digital Object Identifier (DOI)

  • 10.1186/1471-2105-14-S5-S10

PubMed ID

  • 23735126

Additional Document Info

start page

  • S10

volume

  • 14

number

  • SUPPL.5