Impaired Endothelial Progenitor Cell Mobilization and Dysfunctional Bone Marrow Stroma in Diabetes Mellitus Academic Article uri icon

Overview

MeSH Major

  • Bone Marrow
  • Diabetes Mellitus, Experimental
  • Endothelial Cells
  • Hematopoietic Stem Cells
  • Stem Cells

abstract

  • EPC mobilization is impaired under experimental diabetic conditions and our data suggest that diabetes induces alterations in the progenitor cell supportive capacity of the bone marrow stroma, which could be partially responsible for the attenuated EPC mobilization and reduced EPC levels observed in diabetic patients.

publication date

  • March 28, 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3610687

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0060357

PubMed ID

  • 23555959

Additional Document Info

start page

  • e60357

volume

  • 8

number

  • 3