Sublingual tacrolimus: A pharmacokinetic evaluation pilot study Academic Article uri icon

Overview

MeSH Major

  • Immunosuppressive Agents
  • Kidney Failure, Chronic
  • Tacrolimus

abstract

  • An oral-to-sublingual tacrolimus dose conversion should be evaluated on an individual basis. A 1:1 dose conversion may be appropriate in the presence of clotrimazole, whereas a 2:1 oral-to-sublingual conversion may be appropriate when there are no concomitantly interacting drugs. These findings should be investigated further in pharmacokinetic studies conducted in solid organ transplant recipients.

publication date

  • January 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/phar.1149

PubMed ID

  • 23307542

Additional Document Info

start page

  • 31

end page

  • 7

volume

  • 33

number

  • 1