Endocervical glandular neoplasia associated with lobular endocervical glandular hyperplasia is HPV-independent and correlates with carbonic anhydrase-IX expression: A Gynaecological Oncology Group Study Academic Article uri icon

Overview

MeSH Major

  • Antigens, Neoplasm
  • Biomarkers, Tumor
  • Carbonic Anhydrases
  • Hyperplasia
  • Neoplasms, Glandular and Epithelial
  • Papillomavirus Infections
  • Uterine Cervical Neoplasms

abstract

  • Our study suggests that there are different molecular mechanisms of carcinogenesis resulting in CGLs vs LEGHs associated with AIS or GA. There is also a possible link between LEGHs and GAs. Furthermore, CA-IX expression may serve as a useful biomarker for the detection of GAs in the absence of H-HPV infection.

publication date

  • February 19, 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3593541

Digital Object Identifier (DOI)

  • 10.1038/bjc.2012.578

PubMed ID

  • 23299542

Additional Document Info

start page

  • 613

end page

  • 20

volume

  • 108

number

  • 3