A practical algorithmic approach to the diagnosis and management of solitary pulmonary nodules: Part 2: Pretest probability and algorithm Review uri icon


MeSH Major

  • Algorithms
  • Lung Neoplasms
  • Solitary Pulmonary Nodule


  • In this second part of a two-part series, we describe an algorithmic approach to the diagnosis of the solitary pulmonary nodule (SPN). An essential aspect of the evaluation of SPN is determining the pretest probability of malignancy, taking into account the significant medical history and social habits of the individual patient, as well as morphologic characteristics of the nodule. Because pretest probability plays an important role in determining the next step in the evaluation, we describe various methods the physician may use to make this determination. Subsequently, we outline a simple yet comprehensive algorithm for diagnosing a SPN, with distinct pathways for the solid and subsolid SPN.

publication date

  • January 2013



  • Review



  • eng

Digital Object Identifier (DOI)

  • 10.1378/chest.12-1487

PubMed ID

  • 23460161

Additional Document Info

start page

  • 840

end page

  • 6


  • 143


  • 3