18F-FPEB, a PET radiopharmaceutical for quantifying metabotropic glutamate 5 receptors: A first-in-human study of radiochemical safety, biokinetics, and radiation dosimetry Academic Article uri icon

Overview

MeSH Major

  • Brain
  • Nitriles
  • Positron-Emission Tomography
  • Pyridines
  • Receptors, Metabotropic Glutamate

abstract

  • (18)F-FPEB is safe and well tolerated, and its regional cerebral distribution is consistent with previous reports in the literature for metabotropic glutamate receptors. The repeatability of measurement suggests that (18)F-FPEB is suitable for quantifying mGluR5 in humans.

publication date

  • March 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.2967/jnumed.112.107995

PubMed ID

  • 23404089

Additional Document Info

start page

  • 388

end page

  • 96

volume

  • 54

number

  • 3