First-in-man evaluation of 2 high-affinity PSMA-avid small molecules for imaging prostate cancer Academic Article uri icon

Overview

MeSH Major

  • Glutamates
  • Prostatic Neoplasms
  • Urea

abstract

  • (123)I-MIP-1072 and (123)I-MIP-1095 detect lesions in soft tissue, bone, and the prostate gland at as early as 1-4 h. These novel radiolabeled small molecules have excellent pharmacokinetic and pharmacodynamic profiles and warrant further development as diagnostic and potentially when labeled with (131)I therapeutic radiopharmaceuticals.

publication date

  • March 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.2967/jnumed.112.111203

PubMed ID

  • 23303962

Additional Document Info

start page

  • 380

end page

  • 7

volume

  • 54

number

  • 3