Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Lung Neoplasms
  • Small Cell Lung Carcinoma

abstract

  • These data suggest that although ABT-737 can induce autophagy in SCLC, autophagic inhibition by choroquine does not markedly alter in vivo response to ABT-737 in relevant preclinical models, arguing against this as a treatment strategy for SCLC.

publication date

  • March 2, 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3599053

Digital Object Identifier (DOI)

  • 10.1186/1476-4598-12-16

PubMed ID

  • 23452820

Additional Document Info

start page

  • 16

volume

  • 12

number

  • 1