The ALK translocation in advanced non-small-cell lung carcinomas: Preapproval testing experience at a single cancer centre Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Non-Small-Cell Lung
  • Lung Neoplasms
  • Receptor Protein-Tyrosine Kinases
  • Translocation, Genetic

abstract

  • The prevalence of ALK translocation in an unselected population of European patients with advanced NSCLCs was 10%. This alteration was mutually exclusive with EGFR and KRAS mutations, as well as with MET amplification. If multiplexing is considered at the preanalytical phase, lung biopsy specimens are sufficient for performing several predictive assays.

publication date

  • March 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1111/his.12037

PubMed ID

  • 23379755

Additional Document Info

start page

  • 609

end page

  • 16

volume

  • 62

number

  • 4