What are SNPs and haplotypes and how will they help us manage the prevention of adult cancer? Review uri icon

Overview

MeSH

  • Adult
  • Chemoprevention
  • Genetic Variation
  • Humans
  • Pharmacogenetics

MeSH Major

  • Haplotypes
  • Neoplasms
  • Polymorphism, Single Nucleotide

abstract

  • Human genetic variation data are now publicly available on a large scale, from public and private discovery efforts. Datasets from the International Haplotype Map Consortium and Perlegen Sciences provide a level of knowledge about human genetic variation that is unprecedented. In combination with novel high-throughput genotyping technologies, these new resources will allow cancer prevention investigators to identify in a more precise way which genetic subsets of patients are likely to benefit most from chemoprevention and screening interventions.

publication date

  • November 2005

has subject area

  • Adult
  • Chemoprevention
  • Genetic Variation
  • Haplotypes
  • Humans
  • Neoplasms
  • Pharmacogenetics
  • Polymorphism, Single Nucleotide

Research

keywords

  • Journal Article
  • Review

Identity

Language

  • eng

PubMed ID

  • 16221385

Additional Document Info

start page

  • 475

end page

  • 479

volume

  • 7

number

  • 6