Rapid elimination kinetics of free PSA or human kallikrein-related peptidase 2 after initiation of gonadotropin-releasing hormone-antagonist treatment of prostate cancer: Potential for rapid monitoring of treatment responses Academic Article uri icon

Overview

MeSH Major

  • Gonadotropin-Releasing Hormone
  • Kallikreins
  • Oligopeptides
  • Prostate-Specific Antigen
  • Prostatic Neoplasms

abstract

  • The rapid decline of fPSA, iPSA and hK2 after fast induction of castration with degarelix is similar to that reported after prostatectomy and offers a novel, informative method to monitor rapid onset of therapeutic action targeting signaling of the androgen receptor.

publication date

  • November 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3474140

Digital Object Identifier (DOI)

  • 10.1515/cclm-2011-0967

PubMed ID

  • 22718641

Additional Document Info

start page

  • 1993

end page

  • 8

volume

  • 50

number

  • 11