Mir143 expression inversely correlates with nuclear ERK5 immunoreactivity in clinical prostate cancer Academic Article uri icon

Overview

MeSH Major

  • MicroRNAs
  • Mitogen-Activated Protein Kinase 7
  • Prostatic Neoplasms

abstract

  • Although the mechanism for ERK5 activation in CaP remains to be fully elucidated, we have further validated the potential role of mir143 in regulating ERK5 levels in the clinical context. In addition, we demonstrate that the automated counting method for nuclear ERK5 is a clinically useful alterative to observer counting method in patient stratification in the context of ERK5 targeting therapy.

publication date

  • January 15, 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3553517

Digital Object Identifier (DOI)

  • 10.1038/bjc.2012.510

PubMed ID

  • 23321517

Additional Document Info

start page

  • 149

end page

  • 54

volume

  • 108

number

  • 1