Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220 Academic Article uri icon

Overview

MeSH Major

  • Antiviral Agents
  • Contraceptive Devices, Female
  • Drug Carriers
  • Pyrimidinones
  • Silicone Elastomers
  • Simian Acquired Immunodeficiency Syndrome
  • Simian Immunodeficiency Virus

abstract

  • An MC1220-releasing SEVR partially protected macaques from vaginal challenge. Such ring devices are a practical method for providing sustained, coitally independent protection against vaginal exposure to HIV-1.

publication date

  • February 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3543122

Digital Object Identifier (DOI)

  • 10.1093/jac/dks415

PubMed ID

  • 23109186

Additional Document Info

start page

  • 394

end page

  • 403

volume

  • 68

number

  • 2