Acute 5-HT1A autoreceptor knockdown increases antidepressant responses and serotonin release in stressful conditions Academic Article uri icon

Overview

MeSH Major

  • Fluoxetine
  • Receptor, Serotonin, 5-HT1A
  • Serotonin
  • Serotonin Uptake Inhibitors

abstract

  • Together with our previous report, the present results indicate that acute suppression of 5-HT(1A) autoreceptor expression evokes robust antidepressant-like effects, likely mediated by an increased capacity of serotonergic neurons to release 5-HT in stressful conditions.

publication date

  • January 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1007/s00213-012-2795-9

PubMed ID

  • 22820867

Additional Document Info

start page

  • 61

end page

  • 74

volume

  • 225

number

  • 1