Proteomics approaches for the analysis of enriched microbial subpopulations and visualization of complex functional information Article Report uri icon

Overview

MeSH Major

  • Cell Transformation, Viral
  • Oncogenes
  • Receptors, Cell Surface

abstract

  • Advances in the separation of microbial subpopulations and in proteomics technologies have paved the way for the global molecular characterization of microbial cells that share common functional characteristics. Quantitative characterization of the dynamics of microbial proteomes enables an unprecedented view of the adaptive responses of microbes to environmental stimuli or during interaction with other species or host cells. However, the intrinsic complexity of such data requires sophisticated visualization methods for the display, mining, interpretation and efficient exploitation of these data resources. In this review, we discuss how new approaches in data visualization such as streamgraphs, network graphs or Voronoi treemaps are being used in the field to provide new insights into the functional complexity of microbial cells, populations and multispecies consortia. © 2012 Elsevier Ltd.

publication date

  • February 2013

Research

keywords

  • Report

Identity

Digital Object Identifier (DOI)

  • 10.1016/j.copbio.2012.10.009

PubMed ID

  • 23141770

Additional Document Info

start page

  • 112

end page

  • 119

volume

  • 24

number

  • 1